What Are the Challenges in Epigenetic Cancer Research?
Despite its potential, epigenetic cancer research faces several challenges:
- Complexity of epigenetic networks: The intricate interplay between various epigenetic modifications makes it difficult to pinpoint specific changes responsible for cancer. - Heterogeneity of cancer: Different cancer types and even different patients with the same cancer can have unique epigenetic profiles. - Epigenetic plasticity: Epigenetic states can be dynamic and influenced by external factors, complicating therapeutic targeting.