What are the Challenges in Histological Techniques?
Histological techniques come with several challenges, including:
- Artifact Creation: Improper processing can create artifacts that may be mistaken for pathological changes. - Antibody Specificity: In IHC, non-specific binding of antibodies can lead to false-positive results. - Tissue Preservation: Poor fixation can result in tissue degradation, affecting the quality of staining and examination.