What are the Challenges in Quantifying Biomolecules?
Several challenges exist in the quantification of biomolecules in cancer:
Sample Heterogeneity: Tumor samples can be highly heterogeneous, affecting the accuracy of quantification. Low Abundance: Some biomolecules may be present in very low quantities, making detection and quantification difficult. Complexity of Biological Systems: The intricate networks of biomolecules in cancer can complicate quantification efforts. Technical Variability: Differences in sample preparation, instrumentation, and analysis can introduce variability.