What Are the Challenges in Studying RYR1 in Cancer?
Investigating RYR1 in cancer is complicated by several factors:
Complexity of Calcium Signaling: Calcium signaling involves numerous components, making it difficult to isolate the effects of RYR1 alterations. Heterogeneity of Cancer: Cancer is a highly heterogeneous disease. RYR1's role may vary across different cancer types and even among patients with the same cancer. Technical Limitations: Studying RYR1 requires sophisticated tools and techniques, which may not be readily available in all research settings.
