What are the Challenges in Targeting Pro Inflammatory Cytokines?
Despite the potential benefits, targeting pro inflammatory cytokines poses several challenges. One major concern is the systemic suppression of the immune system, which can increase the risk of infections and other complications. Additionally, the redundancy and pleiotropy of cytokine networks mean that blocking one cytokine might not be sufficient to halt tumor progression, as other cytokines can compensate. Therefore, combination therapies and personalized approaches are being studied to overcome these challenges and improve treatment efficacy.
