What are the Challenges in Targeting the STING Pathway?
While the STING pathway holds promise, there are several challenges in targeting it for cancer therapy. One major challenge is the risk of chronic inflammation, which can promote cancer progression. Additionally, the pathway's complexity means that not all tumors may respond to STING activation in the same way. Understanding the specific context in which STING activation will be beneficial is crucial for its successful application in cancer therapy.