Several challenges can impede the reduction of tumor size:
Resistance to Treatment: Tumors can develop resistance to therapies like chemotherapy and targeted drugs, making them less effective over time. Side Effects: Treatments that reduce tumor size often come with significant side effects that can impact the patient's quality of life. Accessibility: Tumors located in hard-to-reach areas may be difficult to treat effectively with surgery or radiation. Heterogeneity: Tumors are often heterogeneous, meaning they contain a mix of cells with different characteristics, making them harder to target uniformly.