What Are the Challenges of DNA Sequencing in Cancer?
Despite its potential, DNA sequencing in cancer research faces several challenges:
Tumor heterogeneity: Cancerous tumors are often composed of multiple subclones with distinct genetic profiles, making it difficult to identify all relevant mutations. Data interpretation: The vast amount of data generated by sequencing requires sophisticated bioinformatics tools to identify clinically relevant mutations. Cost and accessibility: While costs have decreased, comprehensive genomic sequencing can still be expensive and may not be accessible to all patients.
