What are the Challenges of HTS in Cancer Research?
Despite its advantages, HTS also faces several challenges: - Complexity of Cancer Biology: Cancer involves complex pathways making it difficult to identify effective targets. - False Positives/Negatives: High rate of false positives/negatives can lead to wasted resources. - Data Management: Handling and analyzing large datasets require sophisticated software and expertise. - Validation: Hits identified in HTS need further validation in more complex biological systems.