What Are the Challenges of Using Prime Editing in Cancer?
Despite its potential, several challenges need to be addressed before prime editing can be widely used in cancer therapy. One major challenge is the efficient delivery of the prime editor to target cells, particularly in solid tumors. Another issue is ensuring the specificity and accuracy of the edits to avoid off-target effects that could cause unintended consequences. Additionally, the long-term effects and safety of prime editing must be thoroughly evaluated in preclinical and clinical studies.
