What Are the Clinical Implications of the EPR Effect?
The EPR effect has significant clinical implications. It has led to the development of several FDA-approved nanomedicines such as Doxil (liposomal doxorubicin) and Abraxane (albumin-bound paclitaxel). These formulations demonstrate improved therapeutic outcomes and reduced side effects compared to their conventional counterparts. However, ongoing clinical trials are necessary to fully understand and optimize the use of the EPR effect in personalized cancer therapy.
