epigenomics

What Are the Common Epigenetic Changes in Cancer?

Several epigenetic changes are frequently associated with cancer:
DNA Methylation: The addition of a methyl group to the DNA, typically at cytosine bases. Abnormal methylation patterns can silence tumor suppressor genes.
Histone Modification: Chemical changes to histone proteins around which DNA is wrapped. These modifications can alter chromatin structure and gene expression.
Non-Coding RNA: Molecules like microRNAs can regulate gene expression post-transcriptionally and are often dysregulated in cancer.

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