What Are the Challenges in Epigenomic Research in Cancer?
Despite its potential, epigenomic research in cancer faces several challenges:
Complexity: The epigenome is highly complex and dynamic, making it challenging to identify specific changes associated with cancer. Heterogeneity: Tumors are often heterogeneous, containing multiple cell types with distinct epigenetic profiles. This complicates the identification of consistent biomarkers. Technological Limitations: While sequencing technologies have advanced, there is still a need for more sensitive and accurate methods to study the epigenome at a single-cell level.
