What Are the Current Challenges in Targeting Hypoxia?
Despite the potential benefits, targeting hypoxia presents several challenges. The heterogeneity of hypoxia within tumors makes it difficult to effectively target all hypoxic regions. Moreover, the dynamic nature of hypoxia, with fluctuating oxygen levels, complicates the timing and delivery of hypoxia-targeted therapies. Identifying reliable biomarkers and developing more precise delivery systems are ongoing areas of research.
