What are the Current Clinical Trials and Research on BET Inhibitors?
Numerous BET inhibitors are currently undergoing clinical trials. Some of the most well-known BETi include JQ1, OTX015 (MK-8628), and birabresib (OTX015). These trials are exploring their efficacy as monotherapies and in combination with other treatments like chemotherapy, immunotherapy, and targeted therapies. Researchers are also investigating biomarkers that can predict response to BETi, aiming to identify patient populations that would benefit most from these therapies.
