What are the future directions for DNMTis in cancer therapy?
Future research is focused on improving the specificity and efficacy of DNMTis. Combination therapies, where DNMTis are used alongside other cancer treatments, hold promise for overcoming resistance and enhancing therapeutic outcomes. Researchers are also exploring novel DNMTis with better pharmacokinetic properties and reduced side effects. Biomarker studies to identify patients who are most likely to benefit from DNMTi therapy are another critical area of investigation.