What are the future directions for sequencing technologies in cancer?
Future directions include:
- Single-Cell Sequencing: Provides insights into tumor heterogeneity and the microenvironment by analyzing individual cells. - Long-Read Sequencing: Technologies like PacBio and Oxford Nanopore offer longer read lengths, improving the detection of structural variations and complex rearrangements. - Epigenomic Sequencing: Understanding how epigenetic changes, such as DNA methylation and histone modifications, contribute to cancer. - Integration with Other Omics: Combining sequencing data with proteomics, metabolomics, and other omics data for a holistic understanding of cancer biology. - Real-Time Sequencing: Developing faster and more efficient sequencing methods that can be used in clinical settings for immediate decision-making.
