What are the implications of CDKN2A mutations for treatment?
The presence of CDKN2A mutations can influence treatment decisions and prognosis. For example, in melanoma patients, knowing their CDKN2A status can help determine their risk of developing other cancers and guide surveillance strategies. Additionally, certain therapies targeting the CDK4/6 pathway may be more effective in tumors with CDKN2A alterations.
