heterogeneity of the tme

What are the Key Cellular Components of the TME?

Key cellular components include:
Cancer-associated fibroblasts (CAFs): These cells support tumor growth and facilitate invasion.
Immune cells: These include tumor-associated macrophages (TAMs), T-cells, and B-cells, which can either inhibit or promote tumor growth depending on their state and type.
Endothelial cells: These cells form blood vessels that supply nutrients and oxygen to the tumor.
Extracellular Matrix (ECM): Provides structural support and biochemical signals to the tumor cells.

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