The core components of PRC1 include BMI1, RING1A, RING1B, and CBX proteins. Each of these proteins plays a specific role in the complex's function. For example, BMI1 is critical for the complex's stability, while RING1A and RING1B are responsible for the ubiquitination of histone H2A. CBX proteins help in recognizing methylated histones, aiding in the targeting of PRC1 to specific genomic loci.
