What are the Key Signaling Pathways Involved in CSCs?
Several key signaling pathways are implicated in the regulation of CSCs, including the Notch, Wnt, Hedgehog, and PI3K/Akt pathways. These pathways are involved in maintaining CSC properties such as self-renewal, differentiation, and survival. Aberrations in these pathways can contribute to the development and maintenance of CSCs, making them potential targets for therapeutic intervention.
