Despite its benefits, PDT has some limitations. The primary limitation is the depth of light penetration, which restricts its use to surface or near-surface cancers. Not all types of cancers are suitable for PDT, and it may not be effective for large or deeply located tumors. Side effects of PDT can include photosensitivity, where the treated skin becomes highly sensitive to light for several weeks. Patients may experience swelling, pain, or burning sensations in the treated area.
