Despite its advantages, cytopathology has some limitations:
1. Sample Quality: Poor-quality samples can lead to inconclusive or inaccurate results. 2. Limited Scope: While cytopathology can detect abnormal cells, it may not always provide information about the tissue architecture, which is crucial for certain diagnoses. 3. False Negatives/Positives: There is a risk of false-negative or false-positive results, which can lead to misdiagnosis.