What are the Limitations of Morphological Analysis?
While morphological analysis is invaluable, it does have limitations:
Subjectivity: Interpretation can be subjective and may vary between pathologists. Lack of Molecular Insight: Morphology alone does not provide information about the genetic and molecular alterations driving the cancer. Sampling Error: Small or non-representative samples may not capture the full extent of tumor heterogeneity.
To complement morphology, molecular techniques such as genomics and proteomics are increasingly being integrated into cancer diagnostics and research.