What are the Limitations of Organoids and 3D Cell Cultures?
- Complexity and Cost: Creating and maintaining 3D cultures and organoids are more complex and expensive than 2D cultures. - Scalability: Large-scale production of organoids is challenging, limiting their use in high-throughput screening. - Lack of Vascularization: Organoids often lack blood vessels, which are crucial for nutrient delivery and waste removal, potentially limiting their physiological relevance.
