Despite its advantages, PDD has some limitations: - Photosensitizer Side Effects: Some patients may experience side effects from the photosensitizing agent, such as skin photosensitivity. - Limited Tissue Penetration: The light used for excitation has limited tissue penetration, which can restrict the effectiveness of PDD in detecting deeper tumors. - Equipment Requirements: PDD requires specialized equipment and expertise, which may not be available in all medical centers.
