What are the Mechanisms Behind Cancer Cell Motility?
Cancer cell motility is orchestrated by a complex interplay of molecular pathways and cellular structures. Key players include the restructuring of the cytoskeleton, the formation of actin-rich protrusions like lamellipodia and filopodia, and the regulation of cell adhesion molecules. Additionally, signaling pathways such as the Rho GTPases and PI3K/AKT pathways are crucial for modulating motility.
