What Are the Mechanisms Behind Polyphenols' Anticancer Effects?
Polyphenols exert anticancer effects through various mechanisms:
Antioxidant Activity: Polyphenols neutralize free radicals, thus protecting cells from oxidative damage. Anti-inflammatory Effects: They inhibit pro-inflammatory enzymes and cytokines, reducing chronic inflammation, which is a known risk factor for cancer. Modulation of Cell Proliferation: Polyphenols can inhibit the proliferation of cancer cells by interfering with cell cycle regulators. Induction of Apoptosis: They promote programmed cell death in cancer cells, thereby preventing tumor growth. Inhibition of Angiogenesis: Polyphenols can prevent the formation of new blood vessels that tumors need to grow and metastasize.
