The exact mechanisms by which PFOA may cause cancer are not fully understood. However, several hypotheses have been proposed:
1. Genotoxicity: PFOA may cause direct damage to DNA, leading to mutations that can initiate cancer. 2. Oxidative Stress: PFOA exposure may result in the production of reactive oxygen species (ROS), which can damage cellular components and contribute to carcinogenesis. 3. Endocrine Disruption: PFOA can interfere with hormone regulation, potentially leading to hormonal imbalances that promote cancer development. 4. Immune System Modulation: PFOA may alter immune system function, reducing the body's ability to detect and destroy cancer cells.
