While MTAs are effective, they are also associated with significant side effects due to their impact on normal cells that rely on microtubules for essential functions. Common side effects include:
- Neurotoxicity: Peripheral neuropathy is a frequent side effect, particularly with drugs like Paclitaxel and Vincristine. - Myelosuppression: Bone marrow suppression can lead to anemia, leukopenia, and thrombocytopenia, increasing the risk of infections and bleeding. - Gastrointestinal symptoms: Nausea, vomiting, and diarrhea are common, affecting the patient's quality of life.