microtubule targeting agents

What Are the Side Effects of MTAs?

While MTAs are effective, they are also associated with significant side effects due to their impact on normal cells that rely on microtubules for essential functions. Common side effects include:
- Neurotoxicity: Peripheral neuropathy is a frequent side effect, particularly with drugs like Paclitaxel and Vincristine.
- Myelosuppression: Bone marrow suppression can lead to anemia, leukopenia, and thrombocytopenia, increasing the risk of infections and bleeding.
- Gastrointestinal symptoms: Nausea, vomiting, and diarrhea are common, affecting the patient's quality of life.

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