What are the Significant Findings from Cancer Genomic Studies?
Research into cancer genomics has uncovered numerous driver mutations responsible for cancer. Some of the significant findings include:
The discovery of TP53 mutations in over 50% of cancers, highlighting its role as a critical tumor suppressor gene. Identification of BRCA1 and BRCA2 mutations, which are strongly associated with breast and ovarian cancers. Understanding the role of EGFR mutations in non-small cell lung cancer, which has led to targeted therapies.
