What are the Therapeutic Implications of Targeting STAT?
Given the pivotal role of STAT proteins in cancer, targeting this pathway offers promising therapeutic opportunities. Several strategies are being explored, including the development of small-molecule inhibitors, peptidomimetics, and antisense oligonucleotides. For example, STAT3 inhibitors are being investigated in preclinical and clinical settings for their potential to suppress tumor growth and enhance the efficacy of existing cancer therapies.