What Are the Therapeutic Implications of Targeting the Cytoskeleton in Cancer?
Given the critical role of the cytoskeleton in cancer cell behavior, targeting cytoskeletal components and their regulatory proteins presents a promising therapeutic strategy. Drugs that interfere with microtubule dynamics, such as paclitaxel and vinblastine, are already in clinical use. Additionally, inhibitors of actin polymerization and agents that disrupt the function of intermediate filaments are being explored as potential cancer therapies.
