What are the Treatment Options for HNPCC-related Cancers?
Treatment options for HNPCC-related cancers are similar to those for sporadic cancers and may include surgery, chemotherapy, radiation therapy, and targeted therapy. However, the presence of DNA mismatch repair mutations can influence the effectiveness of certain treatments, such as immunotherapy. For example, tumors with high microsatellite instability (MSI-H) often respond well to immune checkpoint inhibitors.
