What are the Treatment Options for KSHV-Associated Diseases?
Treatment strategies vary depending on the specific KSHV-associated condition and the patient's overall health:
- Kaposi's Sarcoma (KS): Options include antiretroviral therapy (for HIV-positive patients), chemotherapy, radiation therapy, and immunotherapy. Local treatments like cryotherapy and laser therapy may also be used for skin lesions. - Primary Effusion Lymphoma (PEL): Treatment typically involves combination chemotherapy, often including drugs like doxorubicin, cyclophosphamide, and etoposide. - Multicentric Castleman's Disease (MCD): Treatment may involve immunomodulatory therapies, such as rituximab, corticosteroids, and antiviral medications.
