IRBs encounter several unique challenges in the context of cancer research:
Balancing Risks and Benefits: Determining the acceptability of risks, especially in early-phase clinical trials where the benefits may be uncertain. Complex Protocols: Cancer studies often involve intricate and multifaceted protocols, requiring thorough and expert review. Vulnerable Populations: Many cancer patients are in vulnerable situations, making ethical considerations and protections even more critical. Evolving Therapies: Rapid advancements in cancer treatments necessitate continuous education and adaptation by IRB members to stay current with new developments.