Several factors can influence cell viability in cancer, including:
Genetic Mutations: Mutations in oncogenes or tumor suppressor genes can alter cell viability. Microenvironment: The surrounding tumor microenvironment can affect nutrient supply, oxygen availability, and immune cell interactions, impacting cell survival. Drug Resistance: Cancer cells can develop resistance to chemotherapy, leading to reduced efficacy and higher viability of malignant cells. Cell Signaling Pathways: Dysregulation of pathways like PI3K/AKT and MAPK can promote cell survival and proliferation.