Several factors influence dose adjustments in cancer treatment:
- Renal and liver function: Impaired kidney or liver function can affect drug metabolism and excretion, necessitating lower doses. - Bone marrow function: Drugs that affect bone marrow can lead to low blood counts, requiring dose reductions. - Age and frailty: Elderly or frail patients may need lower doses due to decreased organ function and increased sensitivity to side effects. - Co-existing conditions: Other medical conditions can affect how a patient tolerates treatment.
