Temperature: Most drugs are sensitive to temperature changes. High temperatures can accelerate degradation, while very low temperatures can cause precipitation. pH Levels: The acidity or alkalinity of the storage environment can affect the stability of the drug, particularly for biologics and other sensitive compounds. Light Exposure: Ultraviolet and visible light can cause photodegradation of certain drugs. Moisture: Humidity can impact the stability of solid dosage forms, leading to hydrolysis and other degradation processes. Packaging: The choice of packaging material can influence drug stability. For example, certain plastics may absorb or react with the drug, while glass can offer better protection against environmental factors.