What Factors Influence Photosensitizer Distribution?
Several factors can influence the distribution of photosensitizers in cancer treatment: - Molecular Size and Structure: Larger molecules may have difficulty penetrating tumor tissues. - Lipophilicity: More lipophilic photosensitizers can better integrate into cell membranes. - Charge: Positively charged molecules may interact with negatively charged cell membranes more readily. - Tumor Type and Location: Different cancers and their locations can affect the uptake and retention of photosensitizers.
