The C-X-C chemokine receptor type 4 (CXCR4) is a receptor protein found on the surface of certain cells. It plays a crucial role in various physiological processes, including immune surveillance, hematopoiesis, and organ development. CXCR4 is activated by its ligand, stromal cell-derived factor-1 (SDF-1), also known as CXCL12.