Fatty Acid Synthase (FASN) is a multi-enzyme protein that plays a crucial role in the synthesis of fatty acids. It catalyzes the formation of long-chain saturated fatty acids from acetyl-CoA and malonyl-CoA in the presence of NADPH. FASN is typically active in tissues with high lipid demands, such as the liver and adipose tissue. However, its overexpression has been observed in various types of cancers, making it a subject of significant interest in oncology research.
