Phosphoinositide 3 Kinase (PI3K) is a family of enzymes involved in cellular functions such as growth, proliferation, differentiation, motility, survival, and intracellular trafficking. These enzymes are critical for various cellular processes and are activated by signals from growth factors, cytokines, and other cellular stimuli. PI3K is divided into three classes, with Class I being the most well-studied in the context of cancer.