Real World Evidence (RWE) refers to the clinical evidence obtained from real-world data (RWD), which is collected outside of conventional randomized controlled trials (RCTs). This data is derived from various sources such as electronic health records (EHRs), patient registries, insurance claims, and patient-generated data. The advent of RWE is transforming the landscape of cancer research and treatment by providing insights that are more reflective of routine clinical practice.