structure activity relationship (sar)

What is Structure-Activity Relationship (SAR)?


The Structure-Activity Relationship (SAR) is a method used in drug discovery to identify the relationship between the chemical structure of a molecule and its biological activity. In the context of cancer, SAR is crucial for the development of effective chemotherapeutic agents. By understanding how different chemical modifications influence a molecule's ability to interact with cancer cells, researchers can design more potent and selective drugs.

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