alt pathway

What is the ALT Pathway?

The Alternative Lengthening of Telomeres (ALT) pathway is a telomere maintenance mechanism that some cancer cells use to maintain their telomere length without the enzyme telomerase. Telomeres are the protective caps at the ends of chromosomes, and their maintenance is crucial for cell division and genomic stability. In the absence of telomere maintenance, cells would eventually reach a state called replicative senescence due to critically short telomeres.

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What is the ALT Pathway?
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