What is the Clinical Relevance of miRNA Profiling?
miRNA profiling has significant clinical implications in cancer. Specific miRNA expression patterns can serve as diagnostic and prognostic markers. For example, the overexpression of miR-21 is associated with poor prognosis in multiple cancers. Moreover, miRNAs can be potential therapeutic targets. Inhibitors of oncogenic miRNAs or mimics of tumor-suppressive miRNAs are being explored as therapeutic strategies.