What is the Difference Between RECIST and iRECIST?
iRECIST is an adaptation of the RECIST criteria designed to better capture responses to immunotherapy. The iRECIST guidelines account for the atypical response patterns often seen with these treatments, such as pseudo-progression, where tumors initially appear to grow before eventually shrinking. iRECIST includes provisions for reassessing patients who initially meet criteria for progressive disease to confirm the progression or identify a delayed response.
