What is the Mechanism of Action of Formins in Cancer?
Formins promote cancer progression through multiple mechanisms. They enhance the formation and elongation of actin filaments, which leads to changes in cell shape and increased motility. This is particularly important in the context of metastasis, where cancer cells need to migrate and invade surrounding tissues. Additionally, formins interact with other proteins involved in signaling pathways that drive cell proliferation and survival, further contributing to cancer development.
