What is the relationship between SCN and tumor growth?
The SCN regulates the timing of cell proliferation and death, processes that are often dysregulated in cancer. Tumor cells can hijack the circadian system to promote their own survival and growth. For example, many cancers exhibit altered expression of circadian genes, leading to uncontrolled cell division and reduced apoptosis. Additionally, the SCN influences the production of hormones like melatonin, which has been shown to possess oncostatic properties, inhibiting cancer cell proliferation and enhancing the efficacy of chemotherapy.
